Which statement best differentiates infectious colitis from an IBD flare?

Which statement best differentiates infectious colitis from an IBD flare?

• A. Infectious colitis often has an acute onset and fever; stool studies help distinguish it from an IBD flare.
• B. IBD flares always present with blood diarrhea.
• C. Stool studies are never helpful in differentiating the two.
• D. Infectious colitis often presents with acute onset and fever; stool studies including culture and C. difficile toxin can help differentiate.

Answer: (D)